Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760113 | 0.91 | PIM1 (0.44) | CCR2FOLH1FABP4ALDH1A1MEN1 | |
| SCHEMBL22760482 | 0.91 | ALDH1A1 (0.43) | CCR2FOLH1FABP4ALDH1A1TP53 | |
| SCHEMBL22747864 | 0.81 | CCR2 (0.46) | CCR2FOLH1FABP4ALDH1A1MEN1 | |
| SCHEMBL22747915 | 0.81 | ALDH1A1 (0.40) | FOLH1FABP4ALDH1A1MEN1KMT2A | |
| SCHEMBL22760408 | 0.78 | PIM1 (0.42) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL22760164 | 0.76 | ALDH1A1 (0.38) | CCR2FOLH1ALDH1A1MEN1KMT2A | |
| SCHEMBL22747827 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL22747903 | 0.75 | RAB9A (0.38) | FABP4ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6902224 | 0.74 | CCR2 (0.67) | CCR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL22760058 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |