Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25764645 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SPHK1 | |
| SCHEMBL26258852 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SPHK1 | |
| SCHEMBL24091665 | 0.83 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL26031106 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SPHK1 | |
| SCHEMBL26254824 | 0.81 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL26031090 | 0.81 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL26255568 | 0.80 | SPHK1 (0.48) | ALDH1A1SPHK1 | |
| SCHEMBL22760372 | 0.79 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL26254819 | 0.79 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL26255183 | 0.79 | ALDH1A1 (0.47) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230272384-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF RETINOCHISIN 1 (RS1) | KORRO BIO, INC. | 2023-08-31 | — | — | US | disclosed |
| US-20230272376-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF METHYL-CPG BINDING PROTEIN 2 (MECP2) | KORRO BIO, INC. | 2023-08-31 | — | — | US | disclosed |
| US-20230272383-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF GAP JUNCTION PROTEIN BETA 2 (GJB2) | KORRO BIO, INC. | 2023-08-31 | — | — | US | disclosed |
| US-20200385713-A1 | RNA-EDITING OLIGONUCLEOTIDES AND USES THEREOF | KORRO BIO, INC. | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385713-A1 | RNA-EDITING OLIGONUCLEOTIDES AND USES THEREOF | ADAR, NSUN3, NSUN2 | ALDH1A1 1396/4885SPHK1 1517/4885 |
| US-20230272384-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF RETINOCHISIN 1 (RS1) | ADAR, YARS1, ADA | ALDH1A1 1196/4885SPHK1 2987/4885 |
| US-20230272383-A1 | METHODS AND COMPOSITIONS FOR THE ADAR-MEDIATED EDITING OF GAP JUNCTION PROTEIN BETA 2 (GJB2) | GJB2, ADAR, GJA1 | ALDH1A1 1489/4885SPHK1 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.