Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23425096 | 0.78 | LMNA (0.65) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL3631323 | 0.78 | ALDH1A1 (0.46) | CA12CA7CA9CA14HCAR2 | |
| SCHEMBL12892831 | 0.76 | LMNA (0.67) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL27894964 | 0.76 | LMNA (0.58) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL1093081 | 0.76 | LMNA (0.67) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL27894963 | 0.76 | LMNA (0.58) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL2275787 | 0.76 | GABRP (0.53) | LMNACA4HCAR2ALDH1A1HDAC8 | |
| SCHEMBL2275790 | 0.76 | GABRP (0.53) | LMNACA4HCAR2ALDH1A1HDAC8 | |
| SCHEMBL27706190 | 0.75 | LMNA (0.53) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL27706189 | 0.75 | LMNA (0.53) | LMNAAKR1B10AKR1B1CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190283-A1 | Fab I Inhibitors | DEBIOPHARM INTERNATIONAL SA (CH) | 2011-08-04 | — | — | US | disclosed |
| CN-1197860-C | FAB I inhibitors | SMITHKLINE BEECHAM CORP (CA) | 2005-04-20 | — | — | CN | disclosed |
| CN-1378542-A | Antigen binding fragment I inhibitors | SMITHKLINE BEECHAM CORP (US) | 2002-11-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190283-A1 | Fab I Inhibitors | SERPINB1, TFPI, TFPI2 | LMNA 3308/4885AKR1B10 2074/4885AKR1B1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.