SCHEMBL22767945

SCHEMBL22767945

COC(=O)C(F)(F)C(F)(F)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
THRB P10828 1/20 0.39
KCNN4 O15554 1/20 0.37
DGAT1 O75907 1/20 0.36
ACLY P53396 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PTPN1 P18031 1/20 0.33
SRC P12931 1/20 0.33
MAPT P10636 1/20 0.33
CTRB1 P17538 1/20 0.32
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
TSHR P16473 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517250 0.89 ALDH1A1 (0.45) ALDH1A1KCNN4DGAT1MEN1KMT2A
SCHEMBL29186298 0.85 THRB (0.52) ALDH1A1THRBKCNN4DGAT1ACLY
SCHEMBL9502603 0.85 THRB (0.46) ALDH1A1THRBKCNN4DGAT1ACLY
SCHEMBL29186295 0.83 THRB (0.56) ALDH1A1THRBKCNN4DGAT1ACLY
Fluoride SCHEMBL11207159 0.83 THRB (0.44) ALDH1A1THRBKCNN4DGAT1ACLY
Fluoride SCHEMBL11206733 0.81 THRB (0.54) ALDH1A1THRBKCNN4DGAT1ACLY
SCHEMBL12445266 0.79 ALDH1A1 (0.44) ALDH1A1KCNN4DGAT1MEN1KMT2A
SCHEMBL10763959 0.79 ALDH1A1 (0.39) ALDH1A1KCNN4DGAT1MEN1KMT2A
SCHEMBL517272 0.78 DGAT1 (0.39) ALDH1A1THRBKCNN4DGAT1MEN1
SCHEMBL1129794 0.78 ALDH1A1 (0.42) ALDH1A1KCNN4DGAT1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127225-A1 ONIUM SALT, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-04-28 US disclosed
WO-2020246143-A1 RADIATION-SENSITIVE RESIN COMPOSITION, RESIST PATTERN FORMATION METHOD, AND COMPOUND JSR株式会社 2020-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220127225-A1 ONIUM SALT, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS CACNA1F, SLC6A5, IDUA ALDH1A1 3860/4885THRB 4466/4885KCNN4 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.