SCHEMBL22771502

SCHEMBL22771502

Fc1cccc(-n2c3ccccc3c3ccccc32)c1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
KDM4E B2RXH2 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
JAK2 O60674 1/20 0.35
BTK Q06187 1/20 0.35
GPR3 P46089 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
G6PD P11413 1/20 0.33
POLB P06746 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
RHEB Q15382 1/20 0.33
MGLL Q99685 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
BACE1 P56817 1/20 0.32
HCAR1 Q9BXC0 1/20 0.32
GRM2 Q14416 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31532948 0.86 ALDH1A1 (0.50) ALDH1A1KDM4EATML3MBTL1BTK
SCHEMBL22931541 0.86 ALDH1A1 (0.50) ALDH1A1KDM4EATML3MBTL1BTK
SCHEMBL24495915 0.84 ALDH1A1 (0.52) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL30634063 0.84 ALDH1A1 (0.52) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL17950310 0.81 ALDH1A1 (0.46) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL31365963 0.81 ALDH1A1 (0.46) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL15316120 0.78 ALDH1A1 (0.50) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL21076138 0.78 ALDH1A1 (0.43) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL28425845 0.78 ALKBH5 (0.46) ALDH1A1KDM4EATML3MBTL1GPR3
SCHEMBL28706095 0.78 KDM4E (0.45) ALDH1A1KDM4EATML3MBTL1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371375-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-16 US disclosed
US-20230371375-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-11-16 US disclosed
US-11818952-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-11818952-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
US-11818952-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
EP-4234562-A1 LIGHT-EMITTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2023-08-30 EP disclosed
US-20230225209-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2023-07-13 US disclosed
US-20230225209-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2023-07-13 US disclosed
WO-2022131780-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 솔루스첨단소재 주식회사 2022-06-23 WO disclosed
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-10-26 US disclosed
CN-112236435-A Polycyclic aromatic compound and multimer thereof 学校法人关西学院 2021-01-15 CN disclosed
US-20200395550-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-17 US disclosed
CN-112086565-A Heterocyclic compound and organic light emitting device including the same 三星显示有限公司 2020-12-15 CN disclosed
CN-110642877-A Condensed cyclic compound and organic light emitting device including the same 三星显示有限公司 2020-01-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11158815-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALDH1A1 325/4885KDM4E 3511/4885ATM 1159/4885
US-11818952-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CRY2 ALDH1A1 21/4885KDM4E 3279/4885ATM 3573/4885
US-20200395550-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CRY2 ALDH1A1 21/4885KDM4E 3279/4885ATM 3573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.