SCHEMBL22772441

SCHEMBL22772441

Cc1c(Nc2ccc(Nc3ccccc3)cc2)cccc1C(C)CC(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.50
HSD17B10 Q99714 5/20 0.50
ALOX15 P16050 4/20 0.50
TSHR P16473 4/20 0.50
ALOX12 P18054 4/20 0.50
CYP3A4 P08684 4/20 0.50
MAPK1 P28482 2/20 0.50
HIF1A Q16665 1/20 0.50
TDP1 Q9NUW8 4/20 0.41
LMNA P02545 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
RECQL P46063 2/20 0.41
ATM Q13315 2/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 3/20 0.41
MAPT P10636 8/20 0.40
MEN1 O00255 6/20 0.40
KMT2A Q03164 6/20 0.40
GAA P10253 6/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367251 0.84 ALDH1A1 (0.50) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL22772442 0.79 ALDH1A1 (0.36) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL8077563 0.76 MAPT (0.50) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL14804257 0.74 ALDH1A1 (0.62) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL15093601 0.72 TDP1 (0.51) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL22772445 0.72 TDP1 (0.54) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL29550941 0.72 TDP1 (0.54) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL30285203 0.72 ALDH1A1 (0.53) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL3689775 0.72 ALDH1A1 (0.51) ALDH1A1HSD17B10ALOX15TSHRALOX12
SCHEMBL28282147 0.72 ALDH1A1 (0.44) ALDH1A1HSD17B10ALOX15TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3983375-B1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES SENNICS CO LTD (CN) 2024-07-24 EP disclosed
US-12024482-B2 Low-pollution antidegradant compound and antidegradant composition and rubber composition comprising the same for tires SENNICS CO., LTD. (CN) 2024-07-02 US disclosed
US-12024482-B2 Low-pollution antidegradant compound and antidegradant composition and rubber composition comprising the same for tires SENNICS CO., LTD. (CN) 2024-07-02 US disclosed
EP-3983375-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES Sennics Co., Ltd. (CN) 2022-04-20 EP disclosed
US-20210230099-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES Sennics Co, Ltd. 2021-07-29 US disclosed
US-20210230099-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES Sennics Co, Ltd. 2021-07-29 US disclosed
US-11008281-B2 Low-pollution antidegradant compound and antidegradant composition and rubber composition comprising the same for tires SENNICS CO., LTD. (CN) 2021-05-18 US disclosed
US-11008281-B2 Low-pollution antidegradant compound and antidegradant composition and rubber composition comprising the same for tires SENNICS CO., LTD. (CN) 2021-05-18 US disclosed
WO-2020248572-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES SENNICS CO., LTD. (CN) 2020-12-17 WO disclosed
US-20200392069-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES SENNICS CO., LTD. 2020-12-17 US disclosed
US-20200392069-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES SENNICS CO., LTD. 2020-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200392069-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES TDP1, POT1, TDP2 ALDH1A1 2367/4885HSD17B10 3213/4885ALOX15 1715/4885
US-11008281-B2 Low-pollution antidegradant compound and antidegradant composition and rubber composition comprising the same for tires TDP1, POT1, TDP2 ALDH1A1 2367/4885HSD17B10 3213/4885ALOX15 1715/4885
US-12024482-B2 Low-pollution antidegradant compound and antidegradant composition and rubber composition comprising the same for tires TDP1, POT1, RIF1 ALDH1A1 2146/4885HSD17B10 3365/4885ALOX15 1926/4885
US-20210230099-A1 LOW-POLLUTION ANTIDEGRADANT COMPOUND AND ANTIDEGRADANT COMPOSITION AND RUBBER COMPOSITION COMPRISING THE SAME FOR TIRES TDP1, POT1, RIF1 ALDH1A1 2146/4885HSD17B10 3365/4885ALOX15 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.