Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708994 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL3689775 | 0.76 | ALDH1A1 (0.51) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL29367251 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL8545771 | 0.73 | MAPT (0.40) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL3337211 | 0.72 | ALDH1A1 (0.51) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL22772441 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL8077563 | 0.71 | MAPT (0.50) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL5706517 | 0.70 | ALDH1A1 (0.44) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL11900726 | 0.70 | CXCR2 (0.51) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 | |
| SCHEMBL5025966 | 0.69 | LMNA (0.50) | ALDH1A1CYP3A4ALOX12ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414958-A | Functionalized rubber composition | 米其林集团总公司 | 2019-03-01 | — | — | CN | disclosed |