Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748730 | 0.67 | MEN1 (0.48) | MAPTSIGMAR1MEN1NPC1RAB9A | |
| SCHEMBL11568355 | 0.67 | MAPT (0.40) | MAPTATMSIGMAR1MEN1NPC1 | |
| SCHEMBL12821098 | 0.65 | SIGMAR1 (0.40) | MAPTSIGMAR1MEN1NPC1RAB9A | |
| SCHEMBL2277437 | 0.63 | SIGMAR1 (0.36) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30309571 | 0.63 | SIGMAR1 (0.39) | MAPTSIGMAR1MEN1NPC1RAB9A | |
| SCHEMBL28485542 | 0.63 | SIGMAR1 (0.39) | MAPTSIGMAR1MEN1NPC1RAB9A | |
| SCHEMBL28975392 | 0.63 | SIGMAR1 (0.39) | MAPTSIGMAR1MEN1NPC1RAB9A | |
| SCHEMBL10966351 | 0.61 | DHFR (0.36) | MAPTATMSHMT2GRM2DHFR | |
| SCHEMBL28062310 | 0.56 | ATM (0.41) | MAPTATMSHMT2GRM2DHFR | |
| SCHEMBL4989931 | 0.56 | NPC1 (0.37) | MAPTSIGMAR1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323092-A | UTILIZING AN ELECTRODE OF AN ALLOY OF GOLD WITH NICKEL, COPPER OR IRON | CORVINUS & ROTH GMBH (DE) | 1982-04-06 | — | — | US | disclosed |