Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | METAP2 | P50579 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | METAP1 | P53582 | 4/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CBFB | Q13951 | 5/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203406 | 0.78 | NPC1 (0.76) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL29306762 | 0.78 | SMN1; SMN2 (0.62) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL3336641 | 0.77 | NPC1 (0.64) | NPC1RAB9AHPGDSMN1; SMN2PKM | |
| SCHEMBL4036858 | 0.75 | PDPK1 (0.64) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL29484592 | 0.74 | METAP2 (1.00) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL29484603 | 0.74 | METAP2 (1.00) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL124947 | 0.74 | METAP2 (1.00) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL29405601 | 0.74 | METAP2 (1.00) | NPC1RAB9AMETAP2HPGDLMNA | |
| SCHEMBL9338775 | 0.73 | METAP2 (0.96) | NPC1RAB9AMETAP2HPGDLMNA | |
| Hydrochloric Acid SCHEMBL2147494 | 0.73 | METAP2 (0.96) | NPC1RAB9AMETAP2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657315-B1 | ORGANIC LIGHT-EMITTING DEVICE | LG CHEMICAL LTD (KR) | 2020-12-16 | — | — | EP | disclosed |