Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | METAP2 | P50579 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | METAP1 | P53582 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 3/20 | 0.62 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794398 | 0.84 | NPC1 (0.68) | SMN1; SMN2NPC1RAB9AHPGDPKM | |
| SCHEMBL19794394 | 0.80 | KDM4E (0.52) | SMN1; SMN2NPC1RAB9AHPGDLMNA | |
| SCHEMBL29306761 | 0.79 | AURKA (0.46) | SMN1; SMN2NPC1RAB9AMETAP2LMNA | |
| SCHEMBL13203406 | 0.79 | NPC1 (0.76) | SMN1; SMN2NPC1RAB9AMETAP2HPGD | |
| SCHEMBL124947 | 0.78 | METAP2 (1.00) | SMN1; SMN2NPC1RAB9AMETAP2HPGD | |
| SCHEMBL29484592 | 0.78 | METAP2 (1.00) | SMN1; SMN2NPC1RAB9AMETAP2HPGD | |
| SCHEMBL29405601 | 0.78 | METAP2 (1.00) | SMN1; SMN2NPC1RAB9AMETAP2HPGD | |
| SCHEMBL29484603 | 0.78 | METAP2 (1.00) | SMN1; SMN2NPC1RAB9AMETAP2HPGD | |
| SCHEMBL12153689 | 0.78 | NPC1 (0.77) | SMN1; SMN2NPC1RAB9AHPGDPKM | |
| SCHEMBL22780449 | 0.78 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AMETAP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228523-A1 | Metal complexes | UDC IRELAND LTD (IE) | 2024-07-11 | — | — | US | disclosed |
| US-20240228523-A1 | Metal complexes | UDC IRELAND LTD (IE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228523-A1 | Metal complexes | MCU, IMMT, SOD1 | SMN1; SMN2 4385/4885NPC1 2572/4885RAB9A 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.