Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SI | P14410 | 3/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22780825 | 1.00 | MGAM (0.36) | MGAMGAASIMGAM2AMY1A | |
| SCHEMBL17160481 | 0.80 | HTR6 (0.41) | MGAMGAASIMGAM2AMY1A | |
| SCHEMBL18552968 | 0.79 | MGAM (0.34) | MGAMGAASIMGAM2 | |
| SCHEMBL1354366 | 0.73 | L3MBTL1 (0.59) | L3MBTL1 | |
| SCHEMBL30081932 | 0.73 | L3MBTL1 (0.59) | L3MBTL1 | |
| SCHEMBL29941031 | 0.72 | CYP2C19 (0.58) | L3MBTL1 | |
| SCHEMBL457569 | 0.72 | CYP2C19 (0.58) | L3MBTL1 | |
| SCHEMBL15647165 | 0.71 | HTR6 (0.44) | MGAMGAASIMGAM2AMY1A | |
| SCHEMBL29660466 | 0.68 | MGAM (0.34) | MGAMGAASIMGAM2 | |
| SCHEMBL794853 | 0.68 | MGAM (0.34) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129372-B1 | AZAQUINAZOLINE INHIBITORS OF ATYPICAL PROTEIN KINASE C | CANCER RESEARCH TECH LTD (GB) | 2020-12-16 | — | — | EP | disclosed |