SCHEMBL227884

SCHEMBL227884

C=C(C=O)C(C)CCC=C(C)C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.48
TSHR P16473 2/20 0.48
ALDH1A1 P00352 3/20 0.44
USP2 O75604 1/20 0.34
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14248094 1.00 ALOX15 (0.48) ALOX15TSHRALDH1A1USP2GLA
SCHEMBL17000464 1.00 ALOX15 (0.48) ALOX15TSHRALDH1A1USP2GLA
SCHEMBL30312065 0.83 ALOX15 (0.33) ALOX15TSHRCYP2D6CYP2C19
SCHEMBL6050618 0.79 ALOX15 (0.52) ALOX15TSHRALDH1A1USP2GLA
SCHEMBL21065790 0.79 ALOX15 (0.50) ALOX15TSHRALDH1A1USP2
SCHEMBL14338167 0.77 ALOX15 (0.48) ALOX15TSHRALDH1A1USP2
SCHEMBL14743706 0.76 PPARG (0.31)
SCHEMBL11869803 0.74 ALOX15 (0.50) ALOX15TSHRALDH1A1USP2GLA
SCHEMBL28167129 0.74 ALOX15 (0.50) ALOX15TSHRALDH1A1USP2GLA
SCHEMBL21954204 0.73 ALOX15 (0.50) ALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1020 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 US claimed
EP-4602141-A1 A FRAGRANCE MIXTURE (VI) Symrise AG (DE) 2025-08-20 EP claimed
CN-119968452-A Perfume mixture (VI) 西姆莱斯股份公司 2025-05-09 CN claimed
EP-4532646-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-04-09 EP claimed
CN-119790128-A Perfume mixture (III) 西姆莱斯股份公司 2025-04-08 CN claimed
US-20250099349-A1 A FRAGRANCE MIXTURE SYMRISE AG (DE) 2025-03-27 US claimed
EP-4519403-A1 A FRAGRANCE MIXTURE (V) Symrise AG (DE) 2025-03-12 EP claimed
EP-4096618-B1 A MIXTURE COMPRISING 1,2-ALKANEDIOLS SYMRISE AG (DE) 2025-01-29 EP claimed
CN-119317695-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
CN-119317696-A Perfume mixture (V) 西姆莱斯股份公司 2025-01-14 CN claimed
US-20080200363-A1 Perfumes, brighteners, insect repellants, flavors, vitamins, fabric softeners, skin care agents; increasing potency, reducing cost PROECTER & GAMBLE COMPANY, THE 2008-08-21 US claimed
WO-2008100601-A2 BENEFIT AGENT DELIVERY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2008-08-21 WO claimed
WO-2008074598-A1 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND MONOCYCLIC OXAZOLIDINES FROM PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2008-06-26 WO claimed
WO-2007087977-A1 1-AZA-3,7-DIOXABICYCLO[3.3.0]OCTANE COMPOUNDS AND THEIR USE AS PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2007-08-09 WO claimed
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions FLEXITRAL, INC. 2006-09-14 US claimed
US-6844302-B1 Encapsulated flavor and fragrance INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2005-01-18 US claimed
US-6126930-A REDUCING TRIGEMINAL STIMULATION FROM AN ATOMIZED ALCOHOL THE PROCTER & GAMBLE COMPANY (US) 2000-10-03 US claimed
CN-1251984-A spray composition PROCTER & GAMBLE (US) 2000-05-03 CN claimed
EP-0986367-A1 SPRAY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-03-22 EP claimed
WO-1998035651-A1 SPRAY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-08-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099349-A1 A FRAGRANCE MIXTURE PTMS, EP300, TRPA1 ALOX15 609/4885TSHR 4083/4885ALDH1A1 967/4885
US-20060205632-A1 Pro-fragrance and pro-flavorant compositions TAS2R10, TAS2R9, OR10J3 ALOX15 451/4885TSHR 2205/4885ALDH1A1 1201/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 ALOX15 67/4885TSHR 2980/4885ALDH1A1 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.