Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22775099 | 0.98 | ALDH1A1 (0.30) | ALDH1A1HPGDSMN1; SMN2NOS3NOS2 | |
| SCHEMBL12607740 | 0.76 | GPR35 (0.33) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22789314 | 0.74 | MAPK1 (0.33) | — | |
| SCHEMBL12607739 | 0.72 | ALDH1A1 (0.30) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12607754 | 0.72 | ALDH1A1 (0.30) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14877786 | 0.72 | ALDH1A1 (0.30) | ALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL22775607 | 0.72 | MAPK1 (0.33) | — | |
| SCHEMBL22775106 | 0.67 | CYP3A4 (0.37) | ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12607748 | 0.67 | CHRNB2 (0.32) | ALDH1A1HPGD | |
| SCHEMBL16272779 | 0.66 | NOS3 (0.36) | ALDH1A1HPGDSMN1; SMN2NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249664-A1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2020-12-17 | — | — | WO | disclosed |