Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | USP8 | P40818 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22789455 | 0.88 | MAOA (0.44) | ACHEMAOAUSP8ALDH1A1TERT | |
| SCHEMBL21647174 | 0.88 | ALDH1A1 (0.47) | ACHEMAOAUSP8KDM4EALDH1A1 | |
| SCHEMBL21668602 | 0.87 | ABCG2 (0.47) | ACHEMAOAUSP8KDM4EALDH1A1 | |
| SCHEMBL21647149 | 0.78 | CYP3A4 (0.63) | USP8ALDH1A1TERTMAPTCYP3A4 | |
| SCHEMBL21668603 | 0.78 | ABCG2 (0.49) | ACHEMAOAUSP8KDM4EALDH1A1 | |
| SCHEMBL22789251 | 0.78 | TERT (0.44) | USP8KDM4ETERTMAPTPOLB | |
| SCHEMBL22772263 | 0.77 | USP8 (0.51) | ACHEUSP8KDM4EALDH1A1TERT | |
| SCHEMBL21647185 | 0.76 | USP8 (0.50) | ACHEMAOAUSP8TERT | |
| SCHEMBL27381294 | 0.69 | MAOA (0.56) | MAOAKDM4EALDH1A1TERTABCG2 | |
| SCHEMBL21668590 | 0.67 | CDK2 (0.54) | KDM4EALDH1A1TERTABCG2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200390755-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390755-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | MAPT, PYGB, SLC6A2 | ACHE 9/4885MAOA 75/4885USP8 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.