Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22790116 | 0.81 | SMN1; SMN2 (0.42) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL22790093 | 0.79 | NR4A2 (0.52) | KDM4EMEN1KMT2AADRB1NR4A2 | |
| SCHEMBL22790109 | 0.77 | KDM4E (0.51) | KDM4EMEN1KMT2ANR4A2LMNA | |
| SCHEMBL7652198 | 0.76 | ACVR1 (0.47) | KDM4EMEN1KMT2AKDRADRB1 | |
| Hydrochloric Acid SCHEMBL27216584 | 0.75 | KDM4E (0.49) | KDM4EMEN1KMT2AKDRADRB1 | |
| SCHEMBL22790352 | 0.75 | NR4A2 (0.48) | KDM4EMEN1KMT2ANR4A2LMNA | |
| SCHEMBL22790396 | 0.75 | NR4A2 (0.46) | MEN1KMT2ANR4A2LMNAALDH1A1 | |
| SCHEMBL35211364 | 0.75 | NR4A2 (0.46) | MEN1KMT2ANR4A2LMNAALDH1A1 | |
| SCHEMBL7229124 | 0.72 | ADRB1 (0.46) | KDRADRB1CHRM2CHRM4CHRM1 | |
| SCHEMBL23044993 | 0.72 | ADRB1 (0.43) | KDM4EMEN1KMT2AKDRADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249064-A1 | COMPOUNDS FOR MODULATING FXR | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2020-12-17 | — | — | WO | disclosed |