Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 12/20 | 0.43 |
| ▸ | BCL9 | O00512 | 11/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | BCL9L | Q86UU0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31490556 | 0.88 | ADRB1 (0.51) | ADRB1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8260952 | 0.84 | TTR (0.46) | ADRB1CTNNB1BCL9TTRCHRM2 | |
| SCHEMBL23662606 | 0.83 | MRGPRX4 (0.49) | — | |
| SCHEMBL6505768 | 0.83 | MAOB (0.43) | TTRMAOB | |
| SCHEMBL19404305 | 0.82 | TTR (0.56) | ADRB1CTNNB1BCL9TTRCHRM2 | |
| SCHEMBL19386229 | 0.82 | MAPT (0.46) | TTR | |
| SCHEMBL6498944 | 0.82 | ABL1 (0.45) | TTR | |
| SCHEMBL19404235 | 0.81 | BCL9 (0.45) | CTNNB1BCL9CHRM3OPRD1 | |
| SCHEMBL19386237 | 0.81 | CHRNB2 (0.55) | ADRB1CTNNB1BCL9TTRCHRM2 | |
| SCHEMBL6506081 | 0.81 | ALDH1A1 (0.42) | TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552018-B1 | As antitumor agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6169086-B1 | AN ANTITUMOR AGENT FOR TREATING TUMOR RESISTANT TO 5-FLUOROURACIL TYPE DRUGS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-1022270-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-07-26 | — | — | EP | disclosed |