Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791152 | 0.92 | PTGDR2 (0.41) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL22791290 | 0.92 | PTGDR2 (0.41) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL22791289 | 0.92 | PTGDR2 (0.41) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL22791200 | 0.83 | PTGER4 (0.39) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL29614446 | 0.81 | PTGER4 (0.53) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL22791369 | 0.81 | PTGER4 (0.53) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL22776660 | 0.81 | PTGER4 (0.53) | SIGMAR1PTGDR2DRD4PTGER4 | |
| SCHEMBL22791147 | 0.80 | CRHR1 (0.45) | ACSL1SIGMAR1POLBDRD4GPR52 | |
| SCHEMBL22791359 | 0.80 | EPHX2 (0.37) | SIGMAR1PTGDR2DRD4 | |
| SCHEMBL22791199 | 0.79 | HTR4 (0.44) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251957-A1 | PROSTAGLANDIN E2 RECEPTOR 4 ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |