Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22791999 | 0.84 | ACHE (0.52) | ACHEMAPTSMN1; SMN2LMNATLR9 | |
| SCHEMBL22792227 | 0.81 | HRH1 (0.48) | METMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6284124 | 0.80 | ACHE (0.54) | ACHEMETSLC2A1CCNT1MAPT | |
| SCHEMBL22791998 | 0.80 | ADRB1 (0.51) | ACHEMAPTALDH1A1 | |
| SCHEMBL8259766 | 0.78 | SMN1; SMN2 (0.55) | ACHEMETMAPTSMN1; SMN2LMNA | |
| SCHEMBL27118797 | 0.77 | ACHE (0.50) | ACHEMETCCNT1MAPTSMN1; SMN2 | |
| SCHEMBL22792199 | 0.77 | GPR119 (0.56) | ACHEMAPTSMN1; SMN2LMNAGPR119 | |
| SCHEMBL15727931 | 0.76 | GPR119 (0.53) | ACHEMAPTSMN1; SMN2LMNAP2RX7 | |
| SCHEMBL22792306 | 0.76 | DDB1 (0.47) | ACHEMETLMNAGPR119TP53 | |
| SCHEMBL671029 | 0.76 | GPR119 (0.57) | ACHEMAPTSMN1; SMN2LMNAGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |