Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792341 | 0.88 | KMT2A (0.51) | KMT2AMEN1ATMNPC1RAB9A | |
| SCHEMBL10127337 | 0.82 | HTR3A (0.49) | RAB9AALDH1A1L3MBTL1PANK3 | |
| SCHEMBL13466366 | 0.82 | CNR2 (0.48) | ALDH1A1MAPTLMNANPSR1PANK3 | |
| SCHEMBL14349207 | 0.82 | PANK3 (0.46) | ALDH1A1MAPTHPGDSMOLMNA | |
| SCHEMBL1911473 | 0.81 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1MAPTGAA | |
| SCHEMBL14924078 | 0.81 | OGA (0.50) | PANK3 | |
| SCHEMBL4547927 | 0.80 | CNR2 (0.50) | ALDH1A1MAPTLMNANPSR1PANK3 | |
| SCHEMBL26027624 | 0.80 | DHFR (0.45) | MAPTSMOMAPK1PANK3KCNH2 | |
| SCHEMBL13102362 | 0.79 | KMT2A (0.57) | KMT2AMEN1ATMNPC1RAB9A | |
| SCHEMBL19001135 | 0.78 | OGA (0.44) | SMOPANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |