Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22792013 | 0.88 | KMT2A (0.54) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL21419435 | 0.83 | HTR3A (0.46) | KMT2ARAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20442906 | 0.83 | HTR3A (0.46) | KMT2ARAB9AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL21202542 | 0.82 | ALDH1A1 (0.52) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL18714256 | 0.82 | ALDH1A1 (0.52) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL13102362 | 0.76 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL2395006 | 0.73 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL13356261 | 0.73 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL29377667 | 0.73 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AATM | |
| SCHEMBL155997 | 0.73 | KMT2A (0.57) | KMT2AMEN1NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020252229-A2 | INHIBITORS OF SARM1 | DISARM THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |