Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 7/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21303626 | 0.83 | ABL1 (0.40) | ALDH1A1HPGDSMN1; SMN2CLK1DYRK1A | |
| SCHEMBL21303622 | 0.76 | LTA4H (0.54) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL22448313 | 0.68 | MAP4K4 (0.52) | ALDH1A1HPGDSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL417328 | 0.65 | CLK4 (0.52) | ALDH1A1CLK1DYRK1ACLK4CYP1A2 | |
| SCHEMBL22448314 | 0.65 | IP6K1 (0.56) | ALDH1A1HTTCYP1A2CYP2D6TSHR | |
| SCHEMBL21303629 | 0.65 | CDC7 (0.51) | HTTMAPK1 | |
| SCHEMBL22440210 | 0.65 | LTA4H (0.52) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4592333 | 0.64 | L3MBTL1 (0.43) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3271551 | 0.63 | KMT2A (0.54) | ALDH1A1HPGDSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21303660 | 0.63 | IP6K1 (0.51) | CLK1DYRK1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392174-A1 | NOVEL INHIBITORS OF BACTERIAL GLUTAMINYL CYCLASES FOR USE IN THE TREATMENT OF PERIODONTAL AND RELATED DISEASES | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392174-A1 | NOVEL INHIBITORS OF BACTERIAL GLUTAMINYL CYCLASES FOR USE IN THE TREATMENT OF PERIODONTAL AND RELATED DISEASES | GMPS, GLS, QPCT | ALDH1A1 3918/4885HPGD 691/4885SMN1; SMN2 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.