Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.57 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25060829 | 0.91 | ALOX5 (0.59) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL22639444 | 0.87 | ALOX5 (0.58) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL297384 | 0.86 | ALOX5 (0.61) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL25634037 | 0.85 | ALOX5 (0.53) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL30874112 | 0.85 | ALOX5 (0.66) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL18736016 | 0.85 | ALOX5 (0.66) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL19547909 | 0.82 | ESR1 (0.67) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL619730 | 0.82 | ESR1 (0.61) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL5005580 | 0.82 | HSD17B1 (0.59) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 | |
| SCHEMBL31411927 | 0.81 | HSD17B1 (0.73) | ALOX5HSD17B1HSD17B2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392259-A1 | ORTHOMETALLATED CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION AND COPOLYMERIZATION | ARZOUMANIDIS GREGORY G (US) | 2020-12-17 | — | — | US | disclosed |