Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.66 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30874112 | 0.89 | ALOX5 (0.66) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL29506854 | 0.86 | ESR2 (0.62) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL21360075 | 0.86 | ESR2 (0.62) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL20169571 | 0.86 | ALOX5 (0.50) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL25634037 | 0.85 | ALOX5 (0.53) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL22795574 | 0.85 | ALOX5 (0.60) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL25060829 | 0.84 | ALOX5 (0.59) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL297384 | 0.82 | ALOX5 (0.61) | ALOX5ESR1ESR2ACMSDHSD17B1 | |
| SCHEMBL18704004 | 0.80 | MCL1 (0.60) | ALOX5ESR2ACMSDHSD17B1HSD17B2 | |
| SCHEMBL29587524 | 0.80 | MCL1 (0.60) | ALOX5ESR2ACMSDHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10982149-B2 | Chiral compounds | MERCK PATENT GMBH (DE) | 2021-04-20 | — | — | US | disclosed |
| WO-2017059942-A1 | CHIRAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-04-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10982149-B2 | Chiral compounds | FANCI, COL1A1, LCP1 | ALOX5 1942/4885ESR1 2493/4885ESR2 3609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.