SCHEMBL297384

SCHEMBL297384

Oc1cccc(O)c1-c1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.61
▸ HSD17B1 P14061 5/20 0.59
▸ HSD17B2 P37059 5/20 0.59
▸ ESR2 Q92731 8/20 0.57
▸ ESR1 P03372 7/20 0.57
▸ HDAC4 P56524 1/20 0.52
▸ HDAC2 Q92769 1/20 0.52
▸ HDAC8 Q9BY41 1/20 0.52
▸ ACMSD Q8TDX5 1/20 0.50
▸ CYP1A2 P05177 5/20 0.49
▸ CYP3A4 P08684 3/20 0.49
▸ CYP2D6 P10635 3/20 0.49
▸ CYP2C9 P11712 3/20 0.49
▸ CYP2B6 P20813 3/20 0.49
▸ CYP2C19 P33261 3/20 0.49
▸ GSTP1 P09211 1/20 0.47
▸ CA1 P00915 1/20 0.44
▸ CA2 P00918 1/20 0.44
▸ CA9 Q16790 1/20 0.44
▸ CTDSP1 Q9GZU7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358215 0.87 ALOX5 (0.52) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL2934548 0.87 ALOX5 (0.52) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL22795574 0.86 ALOX5 (0.60) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL29155013 0.83 ESR2 (0.56) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL19211556 0.82 HDAC4 (0.66) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL18736016 0.82 ALOX5 (0.66) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL25060829 0.81 ALOX5 (0.59) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL26502525 0.80 HDAC4 (0.63) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL12696272 0.80 ALOX5 (0.57) ALOX5HSD17B1HSD17B2ESR2ESR1
SCHEMBL14417404 0.79 HSD17B1 (0.72) ALOX5HSD17B1HSD17B2ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1504048-B1 METHOD OF PREPARING POLYESTERCARBONATES GEN ELECTRIC (US) 2007-11-21 — — EP claimed
EP-1751211-A1 METHOD FOR PREPARING A POLYCARBONATE OLIGOMER MIXTURE AT LOW TEMPERATURE FOR MANUFACTURING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2007-02-14 — — EP claimed
US-7041775-B2 via polymerization catalysts within vessel; for production of molded articles GENERAL ELECTRIC COMPANY (US) 2006-05-09 — — US claimed
WO-2005105890-A1 METHOD FOR PREPARING A POLYCARBONATE OLIGOMER MIXTURE AT LOW TEMPERATURE FOR MANUFACTURING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2005-11-10 — — WO claimed
US-20050234211-A1 Method for preparing a polycarbonate oligomer mixture at low temperature for manufacturing polycarbonate CITIBANK, N.A., AS COLLATERAL AGENT 2005-10-20 — — US claimed
EP-1504048-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-02-09 — — EP claimed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 — — WO claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 — — US claimed
US-10654973-B2 Method for producing polycarbonate SHELL OIL COMPANY (US) 2020-05-19 — — US disclosed
US-10640609-B2 Method for preparing a melt polycarbonate SHELL OIL COMPANY (US) 2020-05-05 — — US disclosed
US-10633487-B2 Inherently healing polycarbonate resins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-28 — — US disclosed
EP-3394146-B1 METHOD FOR PREPARING A MELT POLYCARBONATE SHELL INT RESEARCH (NL) 2019-10-30 — — EP disclosed
EP-3394149-B1 METHOD FOR PRODUCING POLYCARBONATE SHELL INT RESEARCH (NL) 2019-10-30 — — EP disclosed
US-20190040194-A1 INHERENTLY HEALING POLYCARBONATE RESINS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-07 — — US disclosed
EP-1414887-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-05-06 — — EP disclosed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 — — WO disclosed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 — — US disclosed
US-6548623-B2 Melt reaction of bisphenol A and bis-methyl salicyl carbonate using alkali or alkaline earth metal catalyst and quaternary ammonium or phosphonium compound; Fries suppression; by-product inhibition GENERAL ELECTRIC COMPANY 2003-04-15 — — US disclosed
US-20030050427-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY 2003-03-13 — — US disclosed
WO-2003010218-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10640609-B2 Method for preparing a melt polycarbonate PKD1, HSD17B7, DHCR7 ALOX5 2336/4885HSD17B1 26/4885HSD17B2 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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