Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15463724 | 0.79 | NR1H2 (0.40) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL22787248 | 0.78 | POLB (0.36) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL746198 | 0.78 | POLB (0.41) | POLBHCAR2HTTCYP11B1CYP11B2 | |
| SCHEMBL30964464 | 0.75 | CYP11B1 (0.40) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL3647016 | 0.75 | RAB9A (0.39) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL2732538 | 0.73 | CYP1A2 (0.39) | POLBHCAR2KDM4EHTTALOX15 | |
| SCHEMBL29920114 | 0.73 | CYP11B1 (0.49) | POLBHCAR2CYP11B1CYP11B2 | |
| SCHEMBL185547 | 0.73 | CYP11B1 (0.49) | POLBHCAR2CYP11B1CYP11B2 | |
| SCHEMBL433999 | 0.72 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL15474181 | 0.71 | CYP11B1 (0.37) | POLBHCAR2KDM4EHTTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249799-A1 | PYRIDINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-12-17 | — | — | WO | disclosed |