Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487153 | 0.87 | CYP2A6 (0.57) | PLGPLAUCYP2A6IMPDH2KDM4E | |
| SCHEMBL2219992 | 0.81 | PLG (0.68) | PLGPLAUCYP2A6IMPDH2KDM4E | |
| SCHEMBL29951912 | 0.81 | PLG (0.68) | PLGPLAUCYP2A6IMPDH2KDM4E | |
| SCHEMBL2275677 | 0.80 | PLA2G2A (0.44) | CA1CA2CA9PLA2G2AALDH1A1 | |
| SCHEMBL8746137 | 0.76 | CYP2A6 (0.57) | CYP2A6IMPDH2KDM4EALDH1A1MAPT | |
| SCHEMBL1296450 | 0.74 | CA1 (0.63) | CA1CA2CA9PLA2G2AFOLH1 | |
| SCHEMBL1926951 | 0.74 | FOLH1 (0.66) | CA1CA2CA9PLA2G2AFOLH1 | |
| SCHEMBL30791058 | 0.74 | FOLH1 (0.70) | CA1CA2CA9PLA2G2AFOLH1 | |
| SCHEMBL70351 | 0.74 | FOLH1 (0.70) | CA1CA2CA9PLA2G2AFOLH1 | |
| SCHEMBL2557250 | 0.74 | ERN1 (0.59) | CYP2A6IMPDH2KDM4EALDH1A1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | claimed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | claimed |
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | FLI1, API5, MAVS | PLG 2799/4885PLAU 4157/4885CA1 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.