Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.42 |
| ▸ | GABRP | O00591 | 3/20 | 0.42 |
| ▸ | GABRD | O14764 | 3/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.42 |
| ▸ | GABRE | P78334 | 3/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279626 | 0.80 | PLG (0.47) | PLA2G2ACA1CA2CA9GABRA1 | |
| SCHEMBL1558428 | 0.78 | PRKAB2 (0.50) | GABRA1GABRB2GABRB1GABRA3GABRP | |
| SCHEMBL70351 | 0.74 | FOLH1 (0.70) | PLA2G2ACA1CA2CA9FOLH1 | |
| SCHEMBL30791058 | 0.74 | FOLH1 (0.70) | PLA2G2ACA1CA2CA9FOLH1 | |
| SCHEMBL2277951 | 0.72 | KDM4E (0.62) | PLA2G2ACA1CA2CA9FOLH1 | |
| SCHEMBL6419348 | 0.71 | F7 (0.51) | ALDH1A1HPGDHAT1EP300 | |
| SCHEMBL1296450 | 0.71 | CA1 (0.63) | PLA2G2ACA1CA2CA9FOLH1 | |
| SCHEMBL1926951 | 0.71 | FOLH1 (0.66) | PLA2G2ACA1CA2CA9FOLH1 | |
| SCHEMBL28757823 | 0.71 | MDH2 (0.72) | PLA2G2AALDH1A1HPGDMDH2SMN1; SMN2 | |
| SCHEMBL1559466 | 0.70 | HTR3E (0.49) | GABRA1GABRB2GABRB1GABRA3GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | claimed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | claimed |
| US-8455516-B2 | HIV-1 fusion inhibitors and methods | TOURO UNIVERSITY (US) | 2013-06-04 | — | — | US | disclosed |
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | TOURO UNIVERSITY (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190343-A1 | HIV-1 FUSION INHIBITORS AND METHODS | FLI1, API5, MAVS | PLA2G2A 4237/4885CA1 4364/4885CA2 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.