SCHEMBL22797175

SCHEMBL22797175

Clc1cccc2c1C1(c3ccccc3-2)C2CC3CC(C2)CC1C3

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.44
HSD11B1 P28845 4/20 0.37
P2RX7 Q99572 4/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728929 1.00 PDK2 (0.44) PDK2HSD11B1P2RX7KMT2ANPC1
SCHEMBL24627108 1.00 PDK2 (0.44) PDK2HSD11B1P2RX7KMT2ANPC1
SCHEMBL25657022 0.92 PDK2 (0.40) PDK2HSD11B1P2RX7KMT2ANPC1
SCHEMBL25501399 0.86 PDK2 (0.38) PDK2HSD11B1
SCHEMBL24627098 0.84 P2RX7 (0.38) PDK2HSD11B1P2RX7
SCHEMBL25037737 0.84 PDK2 (0.36) PDK2HSD11B1
SCHEMBL24728930 0.83 PDK2 (0.37) PDK2
SCHEMBL25818686 0.83 PDK2 (0.35) PDK2HSD11B1
SCHEMBL24808146 0.83 CYP17A1 (0.33) PDK2HSD11B1
SCHEMBL24626708 0.83 PDK2 (0.45) PDK2HSD11B1P2RX7NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-15 US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 US disclosed
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-11 US disclosed
US-20220388944-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-12-08 US disclosed
US-20220223800-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed
US-11203584-B2 Nitrogen-containing compound, electronic element and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2021-12-21 US disclosed
WO-2021213109-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 (CN) 2021-10-28 WO disclosed
US-20210206741-A1 Nitrogen-containing compound, electronic element and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2021-07-08 US disclosed
WO-2021135456-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
WO-2021128764-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-01 WO disclosed
WO-2021120835-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-06-24 WO disclosed
WO-2020248943-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2020-12-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146030-A1 ARYLAMINE COMPOUND, ELECTRONIC COMPONENT USING SAME AND ELECTRONIC DEVICE OCIAD2, AOC2, OCIAD1 PDK2 1893/4885HSD11B1 2552/4885P2RX7 836/4885
US-20210206741-A1 Nitrogen-containing compound, electronic element and electronic device NOS1, PRMT1, MNS1 PDK2 2866/4885HSD11B1 2831/4885P2RX7 2665/4885
US-20220223800-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE OCIAD2, EMC2, OCIAD1 PDK2 1517/4885HSD11B1 707/4885P2RX7 2567/4885
US-20230183191-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE CNOT1, NXF1, NR2E1 PDK2 4047/4885HSD11B1 3706/4885P2RX7 1686/4885
US-11203584-B2 Nitrogen-containing compound, electronic element and electronic device NOS1, PRMT1, MNS1 PDK2 2866/4885HSD11B1 2831/4885P2RX7 2665/4885
US-20220388944-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS NOM1, MNS1, NOS1 PDK2 3839/4885HSD11B1 2819/4885P2RX7 2110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.