Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | CPA1 | P15085 | 3/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798345 | 1.00 | MME (0.44) | MMEACECPA1ACE2TGFBR1 | |
| SCHEMBL18620682 | 0.83 | GLS (0.39) | MMEGLSDPP4ALDH1A1 | |
| SCHEMBL14185381 | 0.82 | MME (0.41) | MMEACECPA1ACE2GLS | |
| SCHEMBL29454463 | 0.79 | FNTA (0.42) | MMEACECPA1ACE2TGFBR1 | |
| SCHEMBL31679342 | 0.77 | ACE (0.46) | MMEACECPA1ACE2GLS | |
| SCHEMBL16636376 | 0.75 | ALDH1A1 (0.48) | MMEACECPA1ACE2TGFBR1 | |
| SCHEMBL4958339 | 0.75 | TGFBR1 (0.55) | MMEACETGFBR1 | |
| SCHEMBL28996288 | 0.75 | TGFBR1 (0.55) | MMEACETGFBR1 | |
| SCHEMBL7353581 | 0.75 | METAP2 (0.54) | MMEACECPA1ACE2CPB2 | |
| SCHEMBL7357202 | 0.75 | METAP2 (0.54) | MMEACECPA1ACE2CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |