Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681622 | 0.85 | ALDH1A1 (0.57) | HTTALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL6162675 | 0.85 | TP53 (0.49) | HTTALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL22799840 | 0.82 | KMT2A (0.55) | HTTALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL6164214 | 0.81 | NPBWR1 (0.46) | HTTALDH1A1SMN1; SMN2GAAKMT2A | |
| SCHEMBL14711327 | 0.80 | SLC5A1 (0.48) | HTTALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL20274436 | 0.79 | ALDH1A1 (0.50) | HTTALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL22800291 | 0.78 | L3MBTL1 (0.41) | HTTALDH1A1SMN1; SMN2HPGDPDE4D | |
| SCHEMBL2358435 | 0.77 | KMT2A (0.58) | ALDH1A1GAAMAPTHPGDCA1 | |
| SCHEMBL13624226 | 0.77 | PDE4D (0.58) | ALDH1A1SMN1; SMN2MAPTHPGDKMT2A | |
| SCHEMBL9682074 | 0.76 | PDE4B (0.48) | HTTALDH1A1SMN1; SMN2MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | Knobbe, Martens, Olson & Bear, LLP | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392157-A1 | CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF | CAPNS1, CAPN2, CAPN1 | HTT 1041/4885ALDH1A1 3918/4885SMN1; SMN2 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.