Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801423 | 0.98 | THRB (0.39) | THRBHTT | |
| SCHEMBL1435255 | 0.91 | THRB (0.36) | THRBHTT | |
| SCHEMBL22801429 | 0.84 | THRB (0.39) | THRBCA2CA1HTTUSP2 | |
| SCHEMBL22801422 | 0.82 | THRB (0.36) | THRBHTTMAPT | |
| SCHEMBL1435185 | 0.81 | HTT (0.36) | HTT | |
| SCHEMBL11649749 | 0.81 | THRB (0.37) | THRBCA2CA1HTT | |
| SCHEMBL20258482 | 0.81 | THRB (0.37) | THRBHTTMAPTTSHR | |
| SCHEMBL7745324 | 0.81 | HTT (0.30) | HTT | |
| Lithium Ion SCHEMBL14716282 | 0.79 | THRB (0.35) | THRBCA2CA1USP2MAPT | |
| SCHEMBL6752099 | 0.79 | THRB (0.35) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450326-A | Modified polyamine polymers for delivery of biomolecules into cells | 普罗美加公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3986956-A1 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | Promega Corporation (US) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020263825-A1 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | PROMEGA CORPORATION (US) | 2020-12-30 | — | — | WO | disclosed |
| US-20200399660-A1 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | PROMEGA CORPORATION | 2020-12-24 | — | — | US | disclosed |