Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801429 | 0.81 | THRB (0.39) | THRBCA2CA1USP2MAPT | |
| SCHEMBL22801430 | 0.79 | THRB (0.43) | THRBCA2CA1USP2MAPT | |
| SCHEMBL22801422 | 0.79 | THRB (0.36) | THRBMAPT | |
| SCHEMBL20258482 | 0.78 | THRB (0.37) | THRBMAPTTSHR | |
| SCHEMBL11649749 | 0.78 | THRB (0.37) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL22801423 | 0.77 | THRB (0.39) | THRB | |
| SCHEMBL6752099 | 0.76 | THRB (0.35) | THRB | |
| SCHEMBL11647883 | 0.76 | THRB (0.35) | THRB | |
| SCHEMBL14715844 | 0.75 | ALDH1A1 (0.37) | THRBMAPTTSHR | |
| SCHEMBL17626379 | 0.75 | LMNA (0.39) | THRBCA2CA1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828603-B2 | Secondary battery, battery pack, electric vehicle, electric power storage system, power tool, and electronic appliance | SONY CORPORATION (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20130052523-A1 | SECONDARY BATTERY, BATTERY PACK, ELECTRIC VEHICLE, ELECTRIC POWER STORAGE SYSTEM, POWER TOOL, AND ELECTRONIC APPLIANCE | SONY CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |