Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22801429 | 0.98 | THRB (0.39) | THRBHTTMAPT | |
| SCHEMBL2297439 | 0.93 | HTT (0.34) | THRBHTTALDH1A1 | |
| SCHEMBL22735046 | 0.86 | HTT (0.45) | HTT | |
| SCHEMBL18137794 | 0.86 | THRB (0.34) | THRBHTTMAPT | |
| SCHEMBL22801423 | 0.84 | THRB (0.39) | THRBHTT | |
| SCHEMBL13786725 | 0.82 | — | — | |
| SCHEMBL610647 | 0.82 | HTT (0.37) | HTTALDH1A1 | |
| SCHEMBL14715844 | 0.82 | ALDH1A1 (0.37) | THRBHTTALDH1A1KDM4EPOLB | |
| SCHEMBL17626379 | 0.82 | LMNA (0.39) | THRBHTTMAPT | |
| SCHEMBL22801430 | 0.82 | THRB (0.43) | THRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450326-A | Modified polyamine polymers for delivery of biomolecules into cells | 普罗美加公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3986956-A1 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | Promega Corporation (US) | 2022-04-27 | — | — | EP | disclosed |
| WO-2020263825-A1 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | PROMEGA CORPORATION (US) | 2020-12-30 | — | — | WO | disclosed |
| US-20200399660-A1 | MODIFIED POLYAMINE POLYMERS FOR DELIVERY OF BIOMOLECULES INTO CELLS | PROMEGA CORPORATION | 2020-12-24 | — | — | US | disclosed |