Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802896 | 1.00 | LMNA (0.59) | LMNAALDH1A1SIGMAR1CCR3KCNH2 | |
| SCHEMBL22802674 | 0.94 | LMNA (0.63) | LMNAALDH1A1SIGMAR1CCR3 | |
| SCHEMBL22802253 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1CCR3 | |
| SCHEMBL22802250 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1CCR3 | |
| SCHEMBL22802899 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1CCR3 | |
| SCHEMBL25108460 | 0.87 | ALDH1A1 (0.52) | LMNAALDH1A1CCR3KCNH2 | |
| SCHEMBL22802249 | 0.87 | ALDH1A1 (0.54) | LMNAALDH1A1CCR3 | |
| SCHEMBL8106831 | 0.85 | CCR3 (0.64) | LMNASIGMAR1CCR3 | |
| SCHEMBL8106645 | 0.83 | CCR3 (0.66) | LMNASIGMAR1CCR3 | |
| SCHEMBL25109775 | 0.82 | ALDH1A1 (0.54) | LMNAALDH1A1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251969-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |