Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802253 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBATMHRH1 | |
| SCHEMBL22802899 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBATMHRH1 | |
| SCHEMBL22802250 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBATMHRH1 | |
| SCHEMBL22802896 | 0.87 | LMNA (0.59) | ALDH1A1LMNACCR3 | |
| SCHEMBL22802902 | 0.87 | LMNA (0.59) | ALDH1A1LMNACCR3 | |
| SCHEMBL8106831 | 0.86 | CCR3 (0.64) | LMNAPOLBMEN1KMT2ACCR3 | |
| SCHEMBL25108460 | 0.85 | ALDH1A1 (0.52) | ALDH1A1LMNAMEN1KMT2ACCR3 | |
| SCHEMBL8106645 | 0.84 | CCR3 (0.66) | LMNAPOLBMEN1KMT2ACCR3 | |
| SCHEMBL22802254 | 0.83 | ALDH1A1 (0.64) | ALDH1A1LMNAPOLBHRH1MEN1 | |
| SCHEMBL25481035 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1LMNAPOLBATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020251969-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2020-12-17 | — | — | WO | disclosed |