Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8106645 | 0.98 | CCR3 (0.66) | CCR3MC4RSIGMAR1KDM4EMEN1 | |
| SCHEMBL14525251 | 0.87 | MC4R (0.65) | CCR3MC4RSIGMAR1KDM4EMEN1 | |
| SCHEMBL6657649 | 0.87 | CCR3 (0.82) | CCR3MC4RSIGMAR1LMNAPOLB | |
| SCHEMBL22802249 | 0.86 | ALDH1A1 (0.54) | CCR3MEN1KMT2ALMNAPOLB | |
| SCHEMBL22802899 | 0.86 | ALDH1A1 (0.54) | CCR3MEN1KMT2ALMNAPOLB | |
| SCHEMBL22802253 | 0.86 | ALDH1A1 (0.54) | CCR3MEN1KMT2ALMNAPOLB | |
| SCHEMBL22802250 | 0.86 | ALDH1A1 (0.54) | CCR3MEN1KMT2ALMNAPOLB | |
| SCHEMBL22802902 | 0.85 | LMNA (0.59) | CCR3SIGMAR1LMNA | |
| SCHEMBL22802896 | 0.85 | LMNA (0.59) | CCR3SIGMAR1LMNA | |
| SCHEMBL6657455 | 0.85 | CCR3 (0.85) | CCR3MC4RSIGMAR1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632031-B1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 2000-05-03 | — | — | EP | disclosed |
| US-5496853-A | FOR TREATING HYPERCHOLESTEROLEMIA | TEIJIN LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0632031-A1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |