Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20210374 | 1.00 | POLB (0.48) | POLBXIAPCTRB1KMT2AMEN1 | |
| SCHEMBL15216177 | 1.00 | POLB (0.48) | POLBXIAPCTRB1KMT2AMEN1 | |
| SCHEMBL29350646 | 1.00 | POLB (0.48) | POLBXIAPCTRB1KMT2AMEN1 | |
| SCHEMBL30963662 | 0.97 | POLB (0.51) | POLBXIAPCTRB1KMT2AMEN1 | |
| SCHEMBL25404023 | 0.89 | CTRB1 (0.48) | CTRB1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL29211787 | 0.89 | CTRB1 (0.48) | CTRB1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL25404019 | 0.89 | CTRB1 (0.48) | CTRB1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL31500753 | 0.88 | CTRB1 (0.47) | POLBCTRB1KMT2AL3MBTL1TSHR | |
| SCHEMBL29413336 | 0.85 | CTRB1 (0.49) | CTRB1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL30317756 | 0.85 | CTRB1 (0.49) | CTRB1KMT2AL3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200392108-A1 | ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS AND METHODS | IGENICA BIOTHERAPEUTICS, INC. | 2020-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200392108-A1 | ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS AND METHODS | SDCBP, HDGF, CD81 | POLB 4353/4885XIAP 558/4885CTRB1 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.