Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292750 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BPOLBALDH1A1PPARG | |
| SCHEMBL7393691 | 0.86 | ITGB3 (0.60) | ITGB3ITGA2BPOLBKDM4EALDH1A1 | |
| SCHEMBL7424094 | 0.86 | ITGB3 (0.41) | ITGB3ITGA2BPPARGPPARDPPARA | |
| SCHEMBL22804109 | 0.78 | SLC7A5 (0.42) | — | |
| SCHEMBL28233244 | 0.78 | CYP1A2 (0.41) | ALDH1A1PPARGPPARA | |
| SCHEMBL7298868 | 0.78 | ITGB3 (0.37) | ITGB3ITGA2BPOLB | |
| SCHEMBL7106924 | 0.77 | ITGB1 (0.34) | ITGB3PPARAITGB1ITGAV | |
| SCHEMBL9307411 | 0.77 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL7294444 | 0.76 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EGAAMITF | |
| SCHEMBL7299550 | 0.76 | PPARA (0.40) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | claimed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |