Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 6/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615265 | 0.77 | CCR1 (0.54) | TRPV3KIF11 | |
| SCHEMBL22804124 | 0.77 | ADORA1 (0.58) | RAB9AADORA2AADORA1 | |
| SCHEMBL22824639 | 0.75 | TOP1 (0.51) | — | |
| SCHEMBL2615845 | 0.75 | KIF11 (0.45) | TRPV3KIF11RAD51KDM4ELMNA | |
| SCHEMBL1107881 | 0.73 | TRPV3 (0.39) | TRPV3KIF11KDM4E | |
| SCHEMBL27642559 | 0.71 | TRPV3 (0.44) | TRPV3KIF11RAD51LMNATHRB | |
| SCHEMBL1549538 | 0.71 | KIF11 (0.46) | TRPV3KIF11RAD51NPC1ADORA2A | |
| SCHEMBL13906450 | 0.71 | CASP1 (0.42) | TRPV3KIF11RAD51LMNATHRB | |
| SCHEMBL11962309 | 0.71 | CCR1 (0.47) | TRPV3RAB9A | |
| SCHEMBL28316951 | 0.71 | CCR1 (0.39) | KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272417-B | 2-methyl-1, 8-naphthyridine compound and preparation method and application thereof | 五邑大学 | 2021-07-13 | — | — | CN | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |
| WO-2020253415-A1 | 2-METHYL-1,8-NAPHTHYRIDINE COMPOUND, AND PREPARATION METHOD AND APPLICATION THEREFOR | 五邑大学 | 2020-12-24 | — | — | WO | disclosed |