SCHEMBL2280652

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12374006	0.87	LTA4H (0.38)	CYP3A4ROCK1ALDH1A1LTA4H
	SCHEMBL12374014	0.85	F10 (0.39)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL12373986	0.84	NPBWR1 (0.40)	—
	SCHEMBL2276431	0.83	ADRA2C (0.41)	ALDH1A1MAPT
	SCHEMBL12374011	0.82	LNPEP (0.41)	TP53ALDH1A1MEN1KMT2A
	SCHEMBL12373988	0.82	AGXT (0.40)	ALDH1A1MEN1KMT2AKDM4EPOLB
	SCHEMBL12374034	0.81	SMN1; SMN2 (0.36)	TP53ALDH1A1MEN1KMT2AMAPT
	SCHEMBL12374001	0.80	SLC6A4 (0.38)	CYP3A4MAOBALDH1A1MEN1KMT2A
	SCHEMBL12374016	0.80	F10 (0.40)	CYP3A4TP53ALDH1A1KDM4EHSD17B10
	SCHEMBL2388812	0.80	CYP3A4 (0.42)	CYP3A4TP53MAOBROCK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.