Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680154 | 0.80 | ICAM1 (0.39) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL1979487 | 0.79 | CCR5 (0.45) | KDM4CMEN1KMT2ACCR5HPGD | |
| SCHEMBL2006340 | 0.79 | TACR1 (0.45) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4184332 | 0.78 | KDM4C (0.47) | KDM4CMEN1KMT2A | |
| SCHEMBL25221323 | 0.78 | KMT2A (0.57) | HRH3CYP2D6KDM4CMAOBMAOA | |
| SCHEMBL12375129 | 0.77 | KDM4C (0.36) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11258174 | 0.77 | KDM4C (0.46) | KDM4CMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL5940726 | 0.77 | CCR5 (0.49) | KDM4CMEN1KMT2ACCR5RAB9A | |
| SCHEMBL2284090 | 0.77 | L3MBTL1 (0.47) | KDM4CMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10687441 | 0.77 | KDM4C (0.55) | HRH3CYP2D6KDM4CMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970339-B1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | LILLY CO ELI (US) | 2017-08-16 | — | — | EP | disclosed |
| US-9617285-B2 | 1-hydroxy-benzooxaboroles as antiparasitic agents | ELI LILLY AND COMPANY (US) | 2017-04-11 | — | — | US | disclosed |
| US-9493489-B2 | Boron-containing small molecules as anti-protozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-9493489-B2 | Boron-containing small molecules as anti-protozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-9493489-B2 | Boron-containing small molecules as anti-protozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| US-9346834-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346834-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346834-B2 | Boron-containing small molecules as antiprotozoal agents | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-24 | — | — | US | disclosed |
| EP-2970339-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | Eli Lilly and Company (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150353581-A1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2015-12-10 | — | — | US | disclosed |
| US-20120295875-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-20120295875-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-20110207702-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207702-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207702-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| WO-2011049971-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2010045503-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045503-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045505-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045505-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353581-A1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | HAO1, CYP8B1, KMO | HRH3 230/4885CYP2D6 933/4885KDM4C 203/4885 |
| US-20120295875-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS | BTD, BAD, BRI3BP | HRH3 964/4885CYP2D6 3449/4885KDM4C 3993/4885 |
| US-20110207702-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS | BRDT, BRI3BP, BTN3A1 | HRH3 1012/4885CYP2D6 4290/4885KDM4C 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.