Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18570579 | 0.83 | L3MBTL1 (0.46) | SCN8ASCN10AL3MBTL1LMNAMAPT | |
| SCHEMBL23246582 | 0.82 | AR (0.49) | PTGDR2SLC6A4ARKDM4E | |
| SCHEMBL19563647 | 0.82 | SCN8A (0.46) | SCN8ASCN10AL3MBTL1LMNAMAPT | |
| SCHEMBL22809589 | 0.82 | SLC6A4 (0.56) | SCN8ASCN10AL3MBTL1LMNAMAPT | |
| SCHEMBL19563652 | 0.82 | HTR2A (0.51) | SCN8ASCN10APTGDR2L3MBTL1LMNA | |
| SCHEMBL18570517 | 0.82 | L3MBTL1 (0.62) | SCN8ASCN10APTGDR2L3MBTL1LMNA | |
| SCHEMBL276089 | 0.82 | TBXA2R (0.45) | SCN8ASCN10ALMNAMAPTRAB9A | |
| SCHEMBL7138558 | 0.81 | LMNA (0.57) | SCN8ASCN10AL3MBTL1LMNAMAPT | |
| SCHEMBL19524164 | 0.81 | MAPT (0.65) | SCN8ASCN10AL3MBTL1LMNAMAPT | |
| SCHEMBL13997552 | 0.80 | HTR2A (0.50) | SCN8ASCN10APTGDR2KIF11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239134-B1 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2020-12-23 | — | — | EP | disclosed |