Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18570362 | 0.88 | HTR2A (0.52) | SLC6A4HTR2AKCNH2MAPTMAPK1 | |
| SCHEMBL18570517 | 0.88 | L3MBTL1 (0.62) | SLC6A4HTR2AKCNH2MAPTMAPK1 | |
| SCHEMBL18570579 | 0.87 | L3MBTL1 (0.46) | SLC6A4HTR2AKCNH2MAPTL3MBTL1 | |
| SCHEMBL19563652 | 0.85 | HTR2A (0.51) | SLC6A4HTR2AKCNH2MAPTL3MBTL1 | |
| SCHEMBL19563647 | 0.85 | SCN8A (0.46) | SLC6A4HTR2AKCNH2MAPTL3MBTL1 | |
| SCHEMBL7138558 | 0.85 | LMNA (0.57) | MAPTL3MBTL1RAB9ASCN8ASCN10A | |
| SCHEMBL19524164 | 0.85 | MAPT (0.65) | SLC6A4HTR2AKCNH2MAPTMAPK1 | |
| SCHEMBL19563654 | 0.83 | SCN8A (0.47) | SLC6A4HTR2AKCNH2MAPTL3MBTL1 | |
| SCHEMBL9868048 | 0.82 | NPSR1 (0.53) | SLC6A4MAPK1L3MBTL1LMNANPSR1 | |
| SCHEMBL18570588 | 0.82 | MAPT (0.52) | SLC6A4HTR2AKCNH2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3239134-B1 | PYRIDONE AMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2020-12-23 | — | — | EP | disclosed |