Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178407 | 0.85 | TRPM5 (0.56) | TRPM5SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL104554 | 0.84 | TRPM5 (0.52) | TRPM5SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL20843804 | 0.81 | MAOA (0.52) | TRPM5SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL7446567 | 0.80 | TRPM5 (0.51) | TRPM5ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1473418 | 0.79 | TRPM5 (0.50) | TRPM5MAPTLMNAMEN1KMT2A | |
| SCHEMBL7444492 | 0.78 | KLK1 (0.55) | TRPM5 | |
| SCHEMBL1473306 | 0.77 | SMN1; SMN2 (0.53) | TRPM5SMN1; SMN2MAPTRAB9ALMNA | |
| SCHEMBL2699785 | 0.76 | TAAR1 (0.44) | TRPM5SMN1; SMN2RAB9ATP53LMNA | |
| SCHEMBL12498384 | 0.75 | TRPM5 (0.52) | TRPM5MAPTRAB9ATP53ALDH1A1 | |
| SCHEMBL3640996 | 0.75 | TRPM5 (0.46) | TRPM5SMN1; SMN2MAPTRAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381914-B1 | METHOD FOR PURIFYING BENZOPYRAN DERIVATIVE, CRYSTAL FORM THEREOF, AND METHOD FOR PREPARING CRYSTAL FORM | HANLIM PHARMACEUTICAL CO LTD (KR) | 2020-12-23 | — | — | EP | disclosed |