Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20149852 | 1.00 | PTPN1 (0.36) | PTPN1EPHX2ASAH1LMNACYP2C19 | |
| SCHEMBL14725897 | 0.89 | ALDH1A1 (0.40) | PTPN1EPHX2ASAH1LMNACYP2C19 | |
| SCHEMBL18608295 | 0.83 | PTPN1 (0.37) | PTPN1EPHX2ASAH1TSHRFAAH | |
| SCHEMBL14700212 | 0.83 | PTPN1 (0.37) | PTPN1EPHX2ASAH1TSHRFAAH | |
| SCHEMBL14700211 | 0.83 | PTPN1 (0.44) | PTPN1ASAH1LMNATSHRFAAH | |
| SCHEMBL23799216 | 0.81 | FAAH (0.55) | ASAH1LMNAFAAH | |
| SCHEMBL31549547 | 0.81 | PTPN1 (0.42) | PTPN1ASAH1LMNATSHRFAAH | |
| SCHEMBL22821571 | 0.81 | KDM4E (0.44) | EPHX2ASAH1LMNATSHRHPGD | |
| SCHEMBL29331428 | 0.81 | KDM4E (0.44) | EPHX2ASAH1LMNATSHRHPGD | |
| SCHEMBL23869653 | 0.81 | RECQL (0.34) | PTPN1EPHX2ASAH1LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983020-B1 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | TAGWORKS PHARMACEUTICALS B V (NL) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024080872-A1 | STRAINED BICYCLONONENES | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2024-04-18 | — | — | WO | disclosed |
| WO-2023158305-A1 | MASKED IL12 PROTEIN | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-08-24 | — | — | WO | disclosed |
| WO-2020256545-A1 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020256546-A1 | COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020256544-A1 | TETRAZINES FOR HIGH CLICK RELEASE SPEED AND YIELD | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2020-12-24 | — | — | WO | disclosed |