SCHEMBL23869653

SCHEMBL23869653

CC(C)(C)C(=O)CCCC(=O)NCC(O)CO

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.34
EPHX2 P34913 2/20 0.33
PTPN1 P18031 1/20 0.33
ASAH1 Q13510 1/20 0.33
KCNH2 Q12809 1/20 0.33
FAAH O00519 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
AR P10275 1/20 0.32
VDR P11473 1/20 0.32
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25162284 0.83 KDM4E (0.41) RECQLEPHX2ASAH1HPGDLMNA
SCHEMBL22815243 0.81 PTPN1 (0.36) RECQLEPHX2PTPN1ASAH1FAAH
SCHEMBL20149852 0.81 PTPN1 (0.36) RECQLEPHX2PTPN1ASAH1FAAH
SCHEMBL14700211 0.79 PTPN1 (0.44) PTPN1ASAH1FAAHHPGDTSHR
SCHEMBL14700212 0.79 PTPN1 (0.37) EPHX2PTPN1ASAH1FAAHHPGD
SCHEMBL18608295 0.79 PTPN1 (0.37) EPHX2PTPN1ASAH1FAAHHPGD
SCHEMBL31549547 0.77 PTPN1 (0.42) PTPN1ASAH1FAAHHPGDTSHR
SCHEMBL23799216 0.77 FAAH (0.55) ASAH1FAAHLMNA
SCHEMBL24339916 0.76 FAAH (0.58) ASAH1FAAHLMNA
SCHEMBL9061545 0.76 FAAH (0.58) ASAH1FAAHLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230121556-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE TAGWORKS PHARMACEUTICALS B.V. (NL) 2023-04-20 US disclosed
US-20210308207-A1 COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY TAGWORKS PHARMACEUTICALS B.V. (NL) 2021-10-07 US disclosed
US-20210299286-A1 TETRAZINES FOR HIGH CLICK CONJUGATION YIELD IN VIVO AND HIGH CLICK RELEASE YIELD TAGWORKS PHARMACEUTICALS B.V. (NL) 2021-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230121556-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE LTB4R, LTC4S, LTA4H RECQL 1932/4885EPHX2 57/4885PTPN1 3343/4885
US-20210299286-A1 TETRAZINES FOR HIGH CLICK CONJUGATION YIELD IN VIVO AND HIGH CLICK RELEASE YIELD FCER2, SQLE, TTL RECQL 3907/4885EPHX2 112/4885PTPN1 3852/4885
US-20210308207-A1 COMPOUNDS COMPRISING A LINKER FOR INCREASING TRANSCYCLOOCTENE STABILITY VIP, PIN1, QPCT RECQL 4696/4885EPHX2 1965/4885PTPN1 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.