Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2288161 | 0.86 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL1897077 | 0.79 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL1903579 | 0.78 | ALDH1A1 (0.37) | CYP2D6ALDH1A1 | |
| SCHEMBL23080069 | 0.76 | PTPN1 (0.31) | CYP2D6 | |
| SCHEMBL10064112 | 0.75 | PTPN1 (0.31) | — | |
| SCHEMBL14902371 | 0.74 | FKBP1A (0.34) | CYP2D6ALDH1A1TP53TSHR | |
| SCHEMBL25608540 | 0.74 | — | — | |
| SCHEMBL7270614 | 0.70 | CYP2D6 (0.37) | CYP2D6ALDH1A1LMNATP53TSHR | |
| SCHEMBL24996357 | 0.70 | — | — | |
| SCHEMBL1899821 | 0.70 | PTPN1 (0.40) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994273-B2 | Photoactive materials | ROLIC AG (CH) | 2011-08-09 | — | — | US | claimed |
| US-7750185-B2 | Photoactive materials | ROLIC AG (CH) | 2010-07-06 | — | — | US | claimed |
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | ROLIC AG (CH) | 2005-12-29 | — | — | US | claimed |
| EP-1386910-A1 | Photoactive materials | Rolic AG (CH) | 2004-02-04 | — | — | EP | claimed |
| US-8436132-B2 | Photoactive materials | ROLIC AG (CH) | 2013-05-07 | — | — | US | disclosed |
| US-20110236602-A1 | PHOTOACTIVE MATERIALS | ROLIC AG (CH) | 2011-09-29 | — | — | US | disclosed |
| US-7994273-B2 | Photoactive materials | ROLIC AG (CH) | 2011-08-09 | — | — | US | disclosed |
| US-20100272979-A1 | PHOTOACTIVE MATERIALS | ROLIC AG (CH) | 2010-10-28 | — | — | US | disclosed |
| US-7750185-B2 | Photoactive materials | ROLIC AG (CH) | 2010-07-06 | — | — | US | disclosed |
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | ROLIC AG (CH) | 2005-12-29 | — | — | US | disclosed |
| EP-1525182-A1 | PHOTOACTIVE MATERIALS | Rolic AG (CH) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004013086-A1 | PHOTOACTIVE MATERIALS | ROLIC AG (CH) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236602-A1 | PHOTOACTIVE MATERIALS | AOC1, CRY1, CCNA1 | CYP2D6 2278/4885ALDH1A1 129/4885LMNA 1281/4885 |
| US-20050288480-A1 | Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked | C9, F12, DAO | CYP2D6 4238/4885ALDH1A1 1929/4885LMNA 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.