Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816413 | 0.92 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22816846 | 0.91 | KDM4E (0.43) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22816623 | 0.91 | KDM4E (0.43) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22815888 | 0.91 | KDM4E (0.40) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22816619 | 0.89 | KDM4E (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22816807 | 0.89 | CYP19A1 (0.44) | MAPTKDM4EHPGDCYP19A1 | |
| SCHEMBL22815996 | 0.89 | KDM4E (0.45) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22816617 | 0.87 | UCHL1 (0.40) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL22816268 | 0.85 | KDM4E (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD | |
| SCHEMBL25463564 | 0.85 | KDM4E (0.45) | ALDH1A1SMN1; SMN2MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |