SCHEMBL25463564

SCHEMBL25463564

CCOC(=O)c1nnn(Cc2ccc(OC)cc2)c1Oc1ccc(-c2ccc(C3CC(F)(F)C3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
CYP19A1 P11511 7/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
ALDH1A1 P00352 3/20 0.40
UCHL1 P09936 1/20 0.40
POLB P06746 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25465650 0.93 KDM4E (0.43) KDM4EHPGDCYP19A1MAPTSMN1; SMN2
SCHEMBL23319971 0.92 ALOX15 (0.42) KDM4EHPGDMAPTSMN1; SMN2ALDH1A1
SCHEMBL22816619 0.89 KDM4E (0.42) KDM4EHPGDCYP19A1MAPTSMN1; SMN2
SCHEMBL26467810 0.88 CYP19A1 (0.39) KDM4EHPGDCYP19A1MAPTSMN1; SMN2
SCHEMBL22816596 0.87 ALOX15 (0.42) KDM4EHPGDMAPTALDH1A1POLB
SCHEMBL22815996 0.86 KDM4E (0.45) KDM4EHPGDCYP19A1MAPTSMN1; SMN2
SCHEMBL26088232 0.86 S1PR4 (0.40) KDM4EHPGDMAPTSMN1; SMN2ALDH1A1
SCHEMBL25465647 0.85 ALOX15 (0.41) KDM4EHPGDMAPTSMN1; SMN2ALDH1A1
SCHEMBL22816248 0.85 ALDH1A1 (0.45) KDM4EHPGDCYP19A1MAPTSMN1; SMN2
SCHEMBL26467681 0.84 CYP19A1 (0.39) KDM4ECYP19A1MAPTPOLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024215907-A1 CRYSTALLINE FORMS OF A 1H-1,2,3-TRIAZOLE-4-CARBOXYLIC ACID COMPOUND Cantero Therapeutics, Inc. (US) 2024-10-17 WO disclosed
WO-2024212137-A1 CRYSTALLINE FORMS OF A 1H-1, 2, 3-TRIAZOLE-4-CARBOXYLIC ACID COMPOUND Cantero Therapeutics, Inc. (US) 2024-10-17 WO disclosed
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143491-A1 TRIAZOLE GLYCOLATE OXIDASE INHIBITORS XDH, DUOX1, PNPO KDM4E 3502/4885HPGD 116/4885CYP19A1 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.