Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26086645 | 0.90 | ALOX15 (0.41) | KDM4EHPGDSMN1; SMN2POLBCNR2 | |
| SCHEMBL22816248 | 0.89 | ALDH1A1 (0.45) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL22816618 | 0.89 | CNR2 (0.42) | KDM4EHPGDPOLBCNR2RXFP1 | |
| SCHEMBL22816617 | 0.89 | UCHL1 (0.40) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL25463564 | 0.89 | KDM4E (0.45) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL22816846 | 0.88 | KDM4E (0.43) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL22816623 | 0.88 | KDM4E (0.43) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL22816812 | 0.86 | CYP19A1 (0.43) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL25465650 | 0.86 | KDM4E (0.43) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 | |
| SCHEMBL22815996 | 0.85 | KDM4E (0.45) | KDM4EHPGDCYP19A1SMN1; SMN2UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |